Hi Lindsay,
1. Gateway no need to run.
2. Collect system settings in task list SAP_ESH_INITIAL_SETUP_000_CLIENT can be used to set the target client.
3. In S/4HANA target client, run task list SAP_ESH_INITIAL_SETUP_WRK_CLIENT
Notes: The above steps should be done before you configure Fact Sheets. For more information, please refer to http://help.sap.com/disclaimer?site=https://support.sap.com/content/dam/SAAP/Sol_Pack/Library/Configuration/MAA_S4HANAX_… -> 3.6 S/4 HANA System: Generic Configuration for Fact Sheets
Regards,
Ning